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THE EFFECT OF DENERVATION ON THE REGENERATION OF SKELETAL MUSCLE AFTER INJURY

J. H. Saunders 1; and H. A. Sissons 1

1 Institute of Orthopaedics, Royal National Orthopaedic Hospital

1 . The repair of a simple crush injury was studied in rats, in both normally innervated and completely denervated muscle. In each case the histological findings at periods from two hours to thirty-two weeks are described.

2. The denervated muscle showed active and effective repair.

3. A comparison with the findings in normally innervated muscle establishes that the cellular processes of repair do not depend on connections with the central nervous system.
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Hip, Knee, Trauma, Upper limb, Foot & Ankle, Paediatrics, Oncology, Spine, Arthroplasty, General