Logo of The Journal of Bone & Joint Surgery (Br)
Joint Replacement Instrumentation Limited (JRI) Ad
Quick search:        
          Advanced Search
Guest Access | Sign In
This Article
Right arrow Full Text (PDF)
Right arrow Submit a response
Right arrow Alert me when this article is cited
Right arrow Alert me when eLetters are posted
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow My Folders
Right arrow Download to citation manager
Citing Articles
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Beighton, P. H.
Right arrow Articles by Horan, F. T.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Beighton, P. H.
Right arrow Articles by Horan, F. T.

DOMINANT INHERITANCE IN FAMILIAL GENERALISED ARTICULAR HYPERMOBILITY

P. H. Beighton 1; and F. T. Horan 2

1 London, England; the Division of Medical Genetics, Johns Hopkins Hospital, Baltimore, Maryland, United States of America, and the Orthopaedic Department, St Bartholomew's Hospital, London, England
2 Montreal, Canada; the Division of Medical Genetics, Johns Hopkins Hospital, Baltimore, Maryland, United States of America, and the Orthopaedic Department, St Bartholomew's Hospital, London, England

Two individuals with generalised articular hypermobility are described. There are many affected members in both kindreds, and the pedigrees indicate that the disorder is transmitted as an autosomal dominant trait. Orthopaedic complications and deformities are common in one family but absent in the other. It is suggested therefore that the two disorders are distinct and separate genetic entities.
(c) British Editorial Society of Bone and Joint Surgery All Rights Reserved
Registered charity no: 209299     Print ISSN: 0301-620X
Hip, Knee, Trauma, Upper limb, Foot & Ankle, Paediatrics, Oncology, Spine, Arthroplasty, General