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Journal of Bone and Joint Surgery - British Volume, Vol 71-B, Issue 3, 492-497
Copyright © 1989 by British Editorial Society of Bone and Joint Surgery


Articles

Deep vein thrombosis after elective knee surgery. An incidence study in 312 patients

MD Stringer, CA Steadman, AR Hedges, EM Thomas, TR Morley, and VV Kakkar

Thrombosis Research Unit, King's College Hospital, London, England.

The incidence of venous thromboembolism after elective knee surgery has previously been studied almost exclusively in patients receiving total knee replacements, in whom the risk of a deep vein thrombosis is approximately 60%. We report the results of ipsilateral ascending venography in 312 patients undergoing a wide variety of elective knee operations under tourniquet ischaemia, none of whom received any specific prophylaxis against thromboembolism. Total knee replacement was confirmed to carry a high risk with ipsilateral deep vein thrombosis in 56.4% and symptomatic pulmonary embolism in 1.9%. By contrast, arthroscopy was associated with a low incidence of venous thrombosis (4.2%). Meniscectomy, arthrotomy, patellectomy, synovectomy and arthrodesis were all high-risk procedures, particularly in patients over 40 years of age, and were associated with deep vein thrombosis rates of 25% to 67%. On the basis of these findings, we advise prophylaxis against venous thromboembolism in all patients over 40 years of age undergoing elective knee surgery other than arthroscopy.


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C. W. Francis, S. D. Berkowitz, P. C. Comp, J. R. Lieberman, J. S. Ginsberg, G. Paiement, G. R. Peters, A. W. Roth, J. McElhattan, C. W. Colwell Jr., et al.
Comparison of Ximelagatran with Warfarin for the Prevention of Venous Thromboembolism after Total Knee Replacement
N. Engl. J. Med., October 30, 2003; 349(18): 1703 - 1712.
[Abstract] [Full Text] [PDF]



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Hip, Knee, Trauma, Upper limb, Foot & Ankle, Paediatrics, Oncology, Spine, Arthroplasty, General