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Journal of Bone and Joint Surgery - British Volume, Vol 74-B, Issue 1, 101-104
Copyright © 1992 by British Editorial Society of Bone and Joint Surgery

Articles

High calcitonin levels in unconscious polytrauma patients

G De Bastiani, F Mosconi, G Spagnol, A Nicolato, S Ferrari, and F Aprili

Institute of Clinical Chemistry and Microscopy, University of Verona, Italy.

We measured levels of calcitonin and other markers of calcium and phosphorus metabolism in both unconscious and conscious patients after multiple trauma. We found dramatic increases in calcitonin levels in unconscious patients, and smaller increases in conscious patients. In two cases, very high levels, more than 100 x normal, appeared to be related to more rapid healing of bone. Calcitonin levels were highest immediately after admission and decreased over the ensuing two weeks. The possible relationship between unconsciousness and the increased rate of healing of fractures is discussed.




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Hip, Knee, Trauma, Upper limb, Foot & Ankle, Paediatrics, Oncology, Spine, Arthroplasty, General