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Journal of Bone and Joint Surgery - British Volume, Vol 74-B, Issue 5, 686-690
Copyright © 1992 by British Editorial Society of Bone and Joint Surgery


Articles

Destructive spondylo-arthropathy during long-term haemodialysis

M Naito, K Ogata, M Nakamoto, T Goya, and Y Sugioka

Department of Orthopaedic Surgery, Faculty of Medicine, Kyushu University, Fukuoka, Japan.

We reviewed 29 patients who had developed destructive arthropathy of the spine during long-term haemodialysis. Their mean age when haemodialysis began was 43.8 years; at diagnosis they had been dialysed for an average of 8.6 years. In 26 patients, the lesions were between C4 and C7; in six they were between L4 and S1, three having lesions in both regions. Sixteen patients had had previous surgery for carpal tunnel syndrome. Spinal surgery was performed in nine patients with satisfactory results in only five. We demonstrated beta-2 microglobulin amyloid deposits in the discs and surrounding ligaments in all biopsied cases. The natural history and management of this condition are not yet clear.




(c) British Editorial Society of Bone and Joint Surgery All Rights Reserved
Registered charity no: 209299     Print ISSN: 0301-620X
Hip, Knee, Trauma, Upper limb, Foot & Ankle, Paediatrics, Oncology, Spine, Arthroplasty, General