CERAMIC-CERAMIC AND METAL-POLYETHYLENE TOTAL HIP REPLACEMENTSCOMPARISON OF PSEUDOMEMBRANES AFTER LOOSENINGS. Lerouge, BIng, MASc, Doctoral Candidate1; O. Huk, MD, Assistant Professor of Surgery2; LH. Yahia, PhD, Professor and Director of the Group for Research in Biomechanics and Biomaterials1; J. Witvoet, MD, Orthopaedic Surgeon in Chief3; and L. Sedel, MD, Senior Orthopaedic Surgeon3
1 Institute of Biomedical Engineering, École Polytechnique, CP Box 6079, Succ. Centre Ville, Montreal, Canada H3C 3A7. Correspondence should be sent to Dr LH. Yahia. We made a semiquantitative study of the comparative histology of pseudomembranes from 12 loose cemented ceramic-ceramic and 18 metal-polyethylene total hip replacements. We found no significant difference in cellular reaction between the two groups, but there was a major difference in the origin of the particulate debris. In the metal-polyethylene group, polyethylene of articular origin was predominant, while in the ceramic-ceramic group the cellular reaction appeared to be a response to zirconia ceramic particles used to opacify cement used for fixation. Isolation and characterisation of the debris showed that the zirconia particles formed the greatest proportion (76%) in ceramic-ceramic hips, while alumina debris of articular origin formed only 12%. Our study has indicated that aseptic loosening of ceramic cups is not due to a response to debris generated at the articular interface, but to mechanical factors which lead to fragmentation of the cement. This article has been cited by other articles:
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