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Neuropathic arthropathy of the knee associated with an intra-articular neurofibroma in a child

F. Lokiec, MD, Senior Orthopaedic Surgeon1; R. Arbel, MD, Senior Orthopaedic Surgeon1; J. Isakov, MD, Senior Pathologist2; and S. Wientroub, MD, Professor and Head1

1 Department of Paediatric Orthopaedics, Dana Children’s Hospital, Tel-Aviv Medical Centre, 6 Weizmann Street, 64239 Tel-Aviv, Israel.
2 Institute of Pathology and Sackler Faculty of Medicine, Tel-Aviv University, Tel-Aviv, Israel.

Correspondence should be sent to Professor S. Wientroub.

We describe a five-year-old child with neurofibromatosis type I who developed a Charcot knee. Infiltration of the joint by tissue associated with the disease caused damage to the proprioceptive mechanism and resulted in severe joint instability, accelerated destruction and development of neuropathic arthropathy.






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Hip, Knee, Trauma, Upper limb, Foot & Ankle, Paediatrics, Oncology, Spine, Arthroplasty, General