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The musculoskeletal manifestations of Werner’s syndrome

N. P. Walton, FRCS, Orthopaedic Registrar1; T. J. Brammar, FRCS, Orthopaedic Registrar1; and N. P. Coleman, FRCS, Consultant Orthopaedic Surgeon1

1 Department of Orthopaedics, Queen Elizabeth Hospital, Gayton Road, King’s Lynn, Norfolk PE30 4ET, UK.

Correspondence should be sent to Mr N. P. Walton at 53 High Street, Dry Drayton, Cambridge CB3 8BS, UK.

Werner’s syndrome is a rare condition usually presenting as premature ageing in adults. Over a period of 30 years we have followed two siblings with extensive musculoskeletal manifestations including a soft-tissue tumour, insufficiency fractures, nonunion and tendonitis, with associated problems of management. The literature is reviewed.






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Registered charity no: 209299     Print ISSN: 0301-620X
Hip, Knee, Trauma, Upper limb, Foot & Ankle, Paediatrics, Oncology, Spine, Arthroplasty, General