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Journal of Bone and Joint Surgery - British Volume, Vol 84-B, Issue 6,
832-838.
doi: 10.1302/0301-620X.84B6.12776 Copyright © 2002 by British Editorial Society of Bone and Joint Surgery The type of cement and failure of total hip replacementsB. Espehaug, PhD, Statistician1; O. Furnes, MD, Orthopaedic Surgeon1; L. I. Havelin, PhD, Orthopaedic Surgeon1; L. B. Engesæter, PhD, Professor, Orthopaedic Surgeon1; and S. E. Vollset, DrPH, Professor, Statistician2
1 The Norwegian Arthroplasty Register, Department of Orthopaedic Surgery, Haukeland University Hospital, N-5021 Bergen, Norway. Correspondence should be sent to Dr B. Espehaug. Using data from the Norwegian Arthroplasty Register, we have the assessed survival of 17 323 primary Charnley hip prostheses in patients with osteoarthritis based upon the type of cement used for the fixation of the implant. Overall, 9.2% had been revised after follow-up for ten years; 71% of the failures involved aseptic loosening of the femoral component. We observed significantly increased rates of failure for prostheses inserted with CMW1 and CMW3 cements. Using implants fixed with gentamicin-containing Palacos cement as the reference, the adjusted Cox regression failure rate ratios were 1.1 (95% CI 0.9 to 1.4) for implants cemented with plain Palacos, 1.1 (95% CI 0.7 to 1.6) for Simplex, 2.1 (95% 1.5 to 2.9) for gentamicin-containing CMW1, 2.0 (95% CI 1.6 to 2.4) for plain CMW1 and 3.0 (95% CI 2.3 to 3.9) for implants fixed with CMW3 cement. The adjusted failure rate at ten years varied from 5.9% for implants fixed with gentamicin-containing Palacos to 17% for those fixed with CMW3. This article has been cited by other articles:
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