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Journal of Bone and Joint Surgery - British Volume, Vol 84-B, Issue 7,
1050-1052.
doi: 10.1302/0301-620X.84B7.13175 Copyright © 2002 by British Editorial Society of Bone and Joint Surgery Juvenile bone-marrow oedema of the acetabulum treated by iloprostCASE REPORTN. Aigner, MD, Consultant Orthopaedic Surgeon; G. Petje, MD, Consultant Orthopaedic Surgeon; W. Schneider, MD, Consultant Orthopaedic Surgeon; C. Krasny, MD, Resident; F. Grill, MD, Head of Department; and F. Landsiedl, MD, Head of DepartmentFirst, Second and Paediatric Orthopaedic Departments, Orthopaedic Hospital Vienna-Speising, Speisinger Strasse 109, A-1130 Vienna, Austria. Correspondence should be sent to Dr N. Aigner. The bone-marrow oedema syndrome is associated with local vascular disturbances and may be treated either conservatively or by core decompression after which recovery may take several weeks. We describe a 15-year-old girl with bone-marrow oedema of the left acetabulum which was confirmed by MRI. She presented with a four-week history of severe constant pain. Routine blood tests and plain radiographs were normal. She was treated with intravenous infusions of iloprost on five consecutive days (20 µg administered in 500 ml of sodium chloride). Iloprost causes vasodilatation with reduction of capillary permeability and it inhibits platelet aggregation. She had relief from pain at rest after three days of treatment and was completely free from symptoms after two weeks. MRI after six weeks showed almost complete resolution of the marrow oedema and was normal after four months. This is the first report of the pharmacological treatment of the bone-marrow oedema syndrome in children. This article has been cited by other articles:
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