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Journal of Bone and Joint Surgery - British Volume, Vol 85-B, Issue 8,
1182-1189.
doi: 10.1302/0301-620X.85B8.14233 Copyright © 2003 by British Editorial Society of Bone and Joint Surgery Acid-etched microtexture for enhancement of bone growth into porous-coated implantsS. A. Hacking, MEng1; E. J. Harvey, MD, Clinical Assistant Professor1; M. Tanzer, MD, Clinical Associate Professor1; J. J. Krygier, CET, Technical Director2; and J. D. Bobyn, PhD, Associate Professor1
1 Division of Orthopaedics, McGill University, 845 Sherbrooke Street West, Montreal, Quebec H3A 2T5, Canada. Correspondence should be sent to Dr J. D. Bobyn at the Jo Miller Orthopaedic Research Laboratory. We designed an in vivo study to determine if the superimposition of a microtexture on the surface of sintered titanium beads affected the extent of bone ingrowth. Cylindrical titanium intramedullary implants were coated with titanium beads to form a porous finish using commercial sintering techniques. A control group of implants was left in the as-sintered condition. The test group was etched in a boiling acidic solution to create an irregular surface over the entire porous coating. Six experimental dogs underwent simultaneous bilateral femoral intramedullary implantation of a control implant and an acid etched implant. At 12 weeks, the implants were harvested in situ and the femora processed for undecalcified, histological examination. Eight transverse serial sections for each implant were analysed by backscattered electron microscopy and the extent of bone ingrowth was quantified by computer-aided image analysis. The extent of bone ingrowth into the control implants was 15.8% while the extent of bone ingrowth into the etched implants was 25.3%, a difference of 60% that was statistically significant. These results are consistent with other research that documents the positive effect of microtextured surfaces on bone formation at an implant surface. The acid etching process developed for this study represents a simple method for enhancing the potential of commonly available porous coatings for biological fixation.
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