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Journal of Bone and Joint Surgery - British Volume, Vol 86-B, Issue 2, 212-216.
doi: 10.1302/0301-620X.86B2.14362  
Copyright © 2004 by British Editorial Society of Bone and Joint Surgery
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Giant-cell tumour of bone

THE LONG-TERM RESULTS OF TREATMENT BY CURETTAGE AND BONE GRAFT

W. Zhen, MD, Professor; H. Yaotian, MD, PhD, Professor; L. Songjian, MD, Associate Professor; L. Ge, MD, Professor; and W. Qingliang, MD, Professor

Department of Orthopaedics, Xijing Hospital, Fourth Military Medical University, Xian City, Shannxi 710032, China.

Correspondence should be sent to Professor W. Zhen.

Giant-cell tumour of bone (GCT) is a locally benign aggressive tumour. The use of adjuvant agents, such as phenol or liquid nitrogen has been recommended to destroy the remaining tumour cells after curettage, and filling of the defect with methylmethacrylate cement has been advocated. Between 1957 and 1992 we treated 92 patients with a GCT with 50% aqueous zinc chloride solution and bone grafting. Their mean age at the time of surgery was 31 years (15 to 59) and the mean follow-up was 11 years (5 to 31).

Twelve (13%) had a local recurrence and one had a wound infection. Two developed degenerative changes around the knee. Eighty-six (93%) achieved good or excellent function. Three had moderate function, and three needed amputation. Our findings indicate that treatment with an aqueous solution of zinc chloride and reconstructive bone grafting after curettage gives good results.




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Hip, Knee, Trauma, Upper limb, Foot & Ankle, Paediatrics, Oncology, Spine, Arthroplasty, General