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Journal of Bone and Joint Surgery - British Volume, Vol 87-B, Issue 11, 1524-1526.
doi: 10.1302/0301-620X.87B11.16354  
Copyright © 2005 by British Editorial Society of Bone and Joint Surgery
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Incidence of infection with the use of non-irradiated morcellised allograft bone washed at the time of revision arthroplasty of the hip

F. N. K. Kwong, MRCSEd, Clinical Research Fellow1; T. Ibrahim, MRCS(Ed & Eng), Specialist Registrar1; and R. A. Power, FRCSEd(Orth), Consultant Orthopaedic Surgeon1

1 Department of Orthopaedic Surgery, Glenfield Hospital, University Hospitals of Leicester NHS Trust, Groby Road, Leicester LE3 9QP, UK.

Correspondence should be sent to Mr F. N. K. Kwong; e-mail: fcng{at}yahoo.com

Implantation of allograft bone is an integral part of revision surgery of the hip. One major concern with its use is the risk of transmission of infective agents. There are a number of methods of processing allograft bone in order to reduce this risk. One method requires washing the tissue using pulsed irrigation immediately before implantation. We report the incidence of deep bacterial infection in 138 patients (144 revision hip arthroplasties) who had undergone implantation of allograft bone. The bone used was fresh-frozen, non-irradiated and pulse-washed with normal saline before implantation. The deep infection rate at a minimum follow-up of one year was 0.7%. This method of processing appears to be associated with a very low risk of allograft-related bacterial infection.




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G. J. van de Pol, P. D. J. Sturm, C. J. van Loon, C. Verhagen, and B. W. Schreurs
Microbiological cultures of allografts of the femoral head just before transplantation
J Bone Joint Surg Br, September 1, 2007; 89-B(9): 1225 - 1228.
[Abstract] [Full Text] [PDF]


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Hip, Knee, Trauma, Upper limb, Foot & Ankle, Paediatrics, Oncology, Spine, Arthroplasty, General