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Journal of Bone and Joint Surgery - British Volume, Vol 87-B, Issue 11, 1536-1540.
doi: 10.1302/0301-620X.87B11.16608  
Copyright © 2005 by British Editorial Society of Bone and Joint Surgery
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A profile of Perthes’ disease in Greater Glasgow

IS THERE AN ASSOCIATION WITH DEPRIVATION?

S. Sharma, FRCS(G), FRCS(Ed), Specialist Registrar in Orthopaedics1; M. Sibinski, MD, PhD, Clinical Fellow in Orthopaedics1; and D. A. Sherlock, DPhil, FRCS, Consultant1

1 Orthopaedic Surgeon, Royal Hospital for Sick, Children, Dalnair Street, Glasgow G3 8SJ, UK.

Correspondence should be sent to Mr S. Sharma at 47 Shuna Place, Newton Mearns, Glasgow G77 6TN, UK; e-mail: sssharma2{at}yahoo.co.uk

It has been reported that there is an association between Perthes’ disease and poverty. We examined the demographic data of a group of 240 children (263 hips) who presented with Perthes’ disease in Greater Glasgow, where the mean deprivation scores are substantially greater than in the rest of Scotland, to see if this association applied and whether other clues to the aetiology of Perthes’ disease could be found. There were 197 boys and 43 girls; 39 (16.25%) had a family history of Perthes’ disease. Bone age in this series was heavily skewed towards the lower percentiles. The mean number of siblings was 1.9, with 31 (12.9%) being an only child. Maternal age at the birth of the first child showed no preponderance of older mothers. Maternal smoking during and after pregnancy was noted in 132 (55%), which compared with the 52% reported in the population of Greater Glasgow in general. Of the children in our series, 60 (25%) were in social class IV and V. However, this applies to more than half of the population of Greater Glasgow. There was no significant evidence of a preponderance of Perthes’ disease in the most deprived groups. The aetiology of Perthes’ disease is likely to be multifactorial and may include a genetic or deprivation influence resulting in delayed bone age.




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 J Bone Joint Surg BrHome page
C. Dezateux and A. Roposch
The puzzles of Perthes' disease: DEFINITIVE STUDIES OF CAUSAL FACTORS ARE NEEDED
J Bone Joint Surg Br, November 1, 2005; 87-B(11): 1463 - 1464.
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Hip, Knee, Trauma, Upper limb, Foot & Ankle, Paediatrics, Oncology, Spine, Arthroplasty, General