Logo of The Journal of Bone & Joint Surgery (Br)
Quick search:        
          Advanced Search
Guest Access | Sign In
Journal of Bone and Joint Surgery - British Volume, Vol 88-B, Issue 12, 1647-1651.
doi: 10.1302/0301-620X.88B12.17964  
Copyright © 2006 by British Editorial Society of Bone and Joint Surgery
This Article
Right arrow Full Text
Right arrow Full Text (PDF)
Right arrow Submit a response
Right arrow View responses
Right arrow Alert me when this article is cited
Right arrow Alert me when eLetters are posted
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in Web of Science
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow My Folders
Right arrow Download to citation manager
Citing Articles
Right arrow Citing Articles via Web of Science (1)
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Issakov, J.
Right arrow Articles by Merimsky, O.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Issakov, J.
Right arrow Articles by Merimsky, O.

Liposarcoma in adult limbs treated by limb-sparing surgery and adjuvant radiotherapy

J. Issakov, MD, Head of Unit of Musculoskeletal Pathology1; V. Soyfer, MD, Radiation and Medical Oncologist2; Y. Kollender, MD, Orthopaedic Surgeon3; J. Bickels, MD, Orthopaedic Surgeon3; I. Meller, MD, Professor, Head of National Unit of Orthopaedic Oncology3; and O. Merimsky, MD, Professor, Head of Unit of Bone and Soft Tissue Oncology4

1 Department of Pathology
2 Unit of Radiation Therapy, Division of Oncology
3 National Unit of Orthopaedic Oncology
4 Unit of Bone and Soft Tissue Oncology, Tel-Aviv Sourasky Medical Centre, 6 Weizmann Street, Tel-Aviv 64239, Israel.

Correspondence should be sent to Professor O. Merimsky; e-mail: oferm{at}tasmc.health.gov.il

Between December 1995 and March 2003, 38 adult patients with intermediate or high-grade liposarcoma in a limb were treated by limb-sparing surgery and post-operative radiotherapy. The ten-year local recurrence-free survival was 83%, the ten-year metastasis-free survival 61%, the ten-year disease-free survival 51% and the ten-year overall survival 67%. Analysis of failure and success showed no association with the age of the patients, gender, the location of the primary tumour, the type of liposarcoma and the quality of resection.

Our results indicate that liposarcoma may recur even ten years after the end of definitive therapy and may spread to unexpected sites as for soft-tissue sarcoma.




eLetters:

Read all eLetters

Liposarcoma in adult limbs treated by limb-sparing surgery and adjuvant radiotherapy
Hiroshi Hatano, et al.
J Bone Joint Surg Br Online, 22 Feb 2007 [Full text]

(c) British Editorial Society of Bone and Joint Surgery All Rights Reserved
Registered charity no: 209299     Print ISSN: 0301-620X
Hip, Knee, Trauma, Upper limb, Foot & Ankle, Paediatrics, Oncology, Spine, Arthroplasty, General