Logo of The Journal of Bone & Joint Surgery (Br)
Quick search:        
          Advanced Search
Guest Access | Sign In
Journal of Bone and Joint Surgery - British Volume, Vol 89-B, Issue 1, 66-71.
doi: 10.1302/0301-620X.89B1.18058  
Copyright © 2007 by British Editorial Society of Bone and Joint Surgery
This Article
Right arrow Full Text
Right arrow Full Text (PDF)
Right arrow Submit a response
Right arrow Alert me when this article is cited
Right arrow Alert me when eLetters are posted
Right arrow Alert me if a correction is posted
Right arrow Citation Map
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in ISI Web of Science
Right arrow Alert me to new issues of the journal
Right arrow My Folders
Right arrow Download to citation manager
Citing Articles
Right arrow Citing Articles via ISI Web of Science (1)
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Suh, K. T.
Right arrow Articles by Lee, J. S.
Right arrow Search for Related Content
PubMed
Right arrow Articles by Suh, K. T.
Right arrow Articles by Lee, J. S.

Pineal gland metabolism in patients with adolescent idiopathic scoliosis

K. T. Suh, MD, Orthopaedic Surgeon, Professor1; S. S. Lee, MS, Graduate Student2; S. J. Kim, MD, Nuclear Physician, Assistant Professor3; Y. K. Kim, MD, Nuclear Physician, Professor3; and J. S. Lee, MD, Orthopaedic Surgeon, Assistant Professor1

1 Department of Orthopaedic Surgery
2 Department of Environmental Engineering, College of Engineering
3 Department of Nuclear Medicine, Pusan National University, School of Medicine, 1-10 Ami-Dong, Seo-Gu, Pusan 602-739, Korea.

Correspondence should be sent to Dr J. S. Lee; e-mail: jungsublee{at}pusan.ac.kr

The scoliosis observed in chickens after pinealectomy resembles that seen in humans with an adolescent idiopathic scoliosis, suggesting that melatonin deficiency may be responsible. However, to date there have been no studies of pineal gland glucose metabolism in patients with adolescent idiopathic scoliosis that might support this hypothesis.

We examined the excretion of urinary 6-sulfatoxyl-melatonin as well as the glucose metabolism of the pineal gland in 14 patients with an adolescent idiopathic scoliosis and compared them with those of 13 gender-matched healthy controls using F-18 fluorodeoxyglucose brain positron emission tomography. There was no significant difference in the level of urinary 6-sulfatoxyl-melatonin or pineal gland metabolism between the study and the control group. We conclude that permanent melatonin deficiency is not a causative factor in the aetiology of adolescent idiopathic scoliosis.






(c) British Editorial Society of Bone and Joint Surgery All Rights Reserved
Registered charity no: 209299     Print ISSN: 0301-620X
Hip, Knee, Trauma, Upper limb, Foot & Ankle, Paediatrics, Oncology, Spine, Arthroplasty, General