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Journal of Bone and Joint Surgery - British Volume, Vol 89-B, Issue 10, 1379-1381.
doi: 10.1302/0301-620X.89B10.18943  
Copyright © 2007 by British Editorial Society of Bone and Joint Surgery
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Bone and joint tuberculosis

CASES IN BLACKBURN BETWEEN 1988 AND 2005

D. S. Sandher, FRCS(Tr&Orth), Orthopaedic Specialist Registrar1; M. Al-Jibury, MRCP, Respiratory Specialist Registrar2; R. W. Paton, FRCS(Orth), Consultant Orthopaedic Surgeon2; and L. P. Ormerod, MD, DSc(Med), FRCP, Professor of Respiratory Medicine2

1 Stepping Hill Hospital, Poplar Grove, Stockport SK2 7JE, UK.
2 Royal Blackburn Hospital, Blackburn, Lancashire BB2 3HH, UK.

Correspondence should be sent to Mr D. S. Sandher; e-mail: dilrajsandher{at}aol.com

We report 79 cases of bone and joint tuberculosis between 1988 and 2005, eight of which were in the Caucasian population and 71 in the non-white population.

The diagnosis was made in the majority (73.4%) by positive bacteriology and/or histology. The mean age at the time of diagnosis was higher in the Caucasian group at 51.5 years (28 to 66) than in the South Asian group at 36.85 years (12 to 93). Only one patient had previous BCG immunisation.

The spine was the site most commonly affected (44.3%). Surgical stabilisation and/or decompression was performed in 23% of these cases because of cord compression on imaging or the presence of neurological signs.

A six-month course of chemotherapy comprising of an initial two months of rifampicin, isoniazide, pyrazinamide and sometimes ethambutol followed by four months treatment with rifampicin and isoniazide, was successful in all cases without proven drug resistance.






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Registered charity no: 209299     Print ISSN: 0301-620X
Hip, Knee, Trauma, Upper limb, Foot & Ankle, Paediatrics, Oncology, Spine, Arthroplasty, General