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Journal of Bone and Joint Surgery - British Volume, Vol 90-B, Issue 11, 1401-1406.
doi: 10.1302/0301-620X.90B11.20771  
Copyright © 2008 by British Editorial Society of Bone and Joint Surgery
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Methicillin-resistant Staphylococcus aureus in orthopaedic surgery

A. Patel, MD, Fellow in Orthopaedic Trauma1; R. P. Calfee, MD, Assistant Professor2; M. Plante, MD, Fellow in Orthopaedic Trauma1; S. A. Fischer, MD, Associate Professor of Medicine3; N. Arcand, MD, Fellow in Orthopaedic Trauma1; and C. Born, MD, Professor of Orthopaedic Surgery1

1 Department of Orthopaedic Surgery
2 Department of Orthopaedic Surgery, Washington University School of Medicine, 660 South Euclid Avenue, Campus Box 8233, St. Louis, Missouri 63110, USA.
3 Division of Infectious Diseases The Warren Alpert School of Medicine, Brown University, 2 Dudley Street, Suite 200, Providence, Rhode Island 02903, USA.

Correspondence should be sent to Dr A. Patel; e-mail: patel_amar{at}msn.com

Methicillin-resistant Staphylococcus aureus (MRSA) has become a ubiquitous bacterium in both the hospital and community setting. There are two major subclassifications of MRSA, community-acquired and healthcare-acquired, each with differing pathogenicity and management. MRSA is increasingly responsible for infections in otherwise healthy, active adults. Local outbreaks affect both professional and amateur athletes and there is increasing public awareness of the issue. Health-acquired MRSA has major cost and outcome implications for patients and hospitals. The increasing prevalence and severity of MRSA means that the orthopaedic community should have a basic knowledge of the bacterium, its presentation and options for treatment.

This paper examines the evolution of MRSA, analyses the spectrum of diseases produced by this bacterium and presents current prevention and treatment strategies for orthopaedic infections from MRSA.




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D. T. M. Fascia, A. Singanayagam, and J. F. Keating
Methicillin-resistant Staphylococcus aureus in orthopaedic trauma: IDENTIFICATION OF RISK FACTORS AS A STRATEGY FOR CONTROL OF INFECTION
J Bone Joint Surg Br, February 1, 2009; 91-B(2): 249 - 252.
[Abstract] [Full Text] [PDF]


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Hip, Knee, Trauma, Upper limb, Foot & Ankle, Paediatrics, Oncology, Spine, Arthroplasty, General