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Journal of Bone and Joint Surgery - British Volume, Vol 90-B, Issue 3, 292-298.
doi: 10.1302/0301-620X.90B3.20155  
Copyright © 2008 by British Editorial Society of Bone and Joint Surgery
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Surgical site infection with methicillin-resistant Staphylococcus aureus after primary total hip replacement

R. J. Walls, MRCSI, Orthopaedic Research Registrar1; S. J. Roche, MRCS(G), Orthopaedic Specialist Registrar1; A. O’Rourke, RGN, H.Dip.Infection Control Nursing, Infection Control Clinical Nurse Specialist1; and J. P. McCabe, MCh, MMSc, FRCSI, FRCS(Trauma Orth), Consultant Orthopaedic Surgeon1

1 Department of Orthopaedic and Trauma Surgery, Merlin Park University Hospital, Dublin Road, Galway, Ireland.

Correspondence should be sent to Mr R. J. Walls; e-mail: raywalls1{at}hotmail.com

We have analysed the management and clinical outcome of a series of consecutive patients who had a total hip replacement and developed post-operative surgical site infection (SSI) with methicillin-resistant Staphylococcus aureus. The incidence of this infection was 1% over a period of five years. We studied SSI in 15 patients (16 infections) with a mean age of 72.7 years (53 to 81). In all, 12 of the infections occurred early and half of the infections involved the prosthesis, resulting in an increase of 11-fold in the cumulative hospital stay.

Methicillin-resistant Staph. aureus was successfully eradicated in all the patients after a mean follow-up of 53.6 months (25 to 88). Superficial incisional infections resolved after antibiotic therapy alone while deep infections required multiple operative debridements. Attempted retention of the implant in early organ space infections was successful in only one of five patients. Only three patients with implant-level infections obtained a pain-free, functional prosthesis while a further three required excision arthroplasty. We have formulated a protocol of treatment which may serve as a guide in the management of these infections.




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eLetters:

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MRSA prosthetic joint infections: a word of caution for developing countries
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J Bone Joint Surg Br Online, 7 Mar 2008 [Full text]
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J Bone Joint Surg Br Online, 10 Apr 2008 [Full text]
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J Bone Joint Surg Br Online, 15 Apr 2008 [Full text]
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Hip, Knee, Trauma, Upper limb, Foot & Ankle, Paediatrics, Oncology, Spine, Arthroplasty, General