Logo of The Journal of Bone & Joint Surgery (Br)
Joint Replacement Instrumentation Limited (JRI) Ad
Quick search:        
          Advanced Search
Guest Access | Sign In
Journal of Bone and Joint Surgery - British Volume, Vol 90-B, Issue 7, 929-933.
doi: 10.1302/0301-620X.90B7.20348  
Copyright © 2008 by British Editorial Society of Bone and Joint Surgery
This Article
Right arrow Full Text
Right arrow Full Text (PDF)
Right arrow Submit a response
Right arrow Alert me when this article is cited
Right arrow Alert me when eLetters are posted
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in ISI Web of Science
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow My Folders
Right arrow Download to citation manager
Google Scholar
Right arrow Articles by Billing, V.
Right arrow Articles by Rydholm, A.
PubMed
Right arrow PubMed Citation
Right arrow Articles by Billing, V.
Right arrow Articles by Rydholm, A.

Deep-seated ordinary and atypical lipomas

HISTOPATHOLOGY, CYTOGENETICS, CLINICAL FEATURES, AND OUTCOME IN 215 TUMOURS OF THE EXTREMITY AND TRUNK WALL

V. Billing, MD, Resident in Orthopaedic Surgery1; F. Mertens, MD, Professor of Clinical Genetics2; H. A. Domanski, MD, Assistant Professor of Histopathology3; and A. Rydholm, MD, Professor of Orthopaedic Oncology4

1 Department of Orthopaedic Surgery, Ängelholm Hospital, SE-262 81, Ängelholm, Sweden.
2 Department of Clinical Genetics
3 Department of Cytology and Pathology
4 Department of Orthopaedic Surgery, Lund University Hospital, SE-221 85, Lund, Sweden.

Correspondence should be sent to Professor A. Rydholm; e-mail: anders.rydholm{at}med.lu.se

Deep-seated lipomas are often atypical histologically and are considered by some to have a high risk of recurrence after excision. We reviewed 215 deep-seated lipomas of the extremities and trunk wall with reference to histology, cytogenetics, clinical features and local recurrence. We classified tumours with atypical features and/or ring chromosomes as atypical lipomas. These were more common in men, larger than ordinary lipomas and more often located in the upper leg. The annual incidence was estimated as ten per million inhabitants and the ratio of atypical to ordinary lipomas was 1:3. In total, six tumours (3%), recurred locally after a median of eight years (1 to 16); of these, four were classified as atypical.

The low recurrence rate of deep-seated lipomas of the extremity or trunk wall, irrespective of histological subtype, implies that if surgery is indicated, the tumour may be shelled out, that atypical lipomas in these locations do not deserve the designation well-differentiated liposarcoma, and that routine review after surgery is not required.






(c) British Editorial Society of Bone and Joint Surgery All Rights Reserved
Registered charity no: 209299     Print ISSN: 0301-620X
Hip, Knee, Trauma, Upper limb, Foot & Ankle, Paediatrics, Oncology, Spine, Arthroplasty, General