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Analysis of the outcome in male and female patients using a unisex total knee replacement system

¹ Towson Orthopaedic Associates, 8322 Bellona Avenue, Baltimore, Maryland 21204, USA.
² OrthoCarolina Hip and Knee Center, 1915 Randolph Road, Charlotte, North Carolina 28207, USA.
³ DePuy Orthopaedics, 700, Orthopaedic Drive, Warsaw, Indiana 46582, USA.

Correspondence should be sent to Dr D. F. Dalury, c/o Elaine P. Henze; e-mail: ehenze1{at}jhmi.edu

Gender-specific total knee replacement has generated much interest recently. We reviewed 1970 Sigma knees implanted in 920 women and 592 men with a mean age of 69.7 years.

At a mean follow-up of 7.3 years (minimum, five years), we found minimal differences in the outcome between genders. At the final follow-up, men had a higher overall Knee Society score and more osteolysis (3.8% vs 1.1%). However, there were no significant differences between men and women in terms of complications or improvements in knee function, pain score or range of movement. The estimated ten-year survivorship was 97% in women and 98% in men (p = 0.96).

We concluded that there was little difference in outcome between the genders treated by a modern unisex design of total knee replacement in this large multicentre study.